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Special Semester on Quantitative Biology analyzed by Mathematical Methods
Linz, October 1, 2007 - January 27, 2008
Representing Biochemical Systems as Collectives of Interacting Automata

Workshop on Systems Biology, Thu, 08 Nov, 2007

Speaker: Luca Cardelli

Abstract

We investigate an artificial biochemistry that operates according to the laws of well-mixed solutions, where each molecule is represented by an interacting automaton. We provide translations between the process algebra or such automata and systems of chemical reactions. We show that the translations preserve discrete-state (stochastic/CME) and continuous-state (concentration/ODE) semantics, and that the process algebra representations are in general more compact by an n-square factor. Compactness and compositionality of representation are essential in describing the large models that arise in Systems Biology.

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