Special Semester on Quantitative Biology analyzed by Mathematical Methods
Linz, October 1, 2007 - January 27, 2008
Events: Workshop on
Ion Channels|Systems Biology|Bioimaging I|Bioimaging II/PDEs|Biomechanics and Chemotaxis|Pattern Formation and Functional Morphology
Workshop on Systems Biology, November 5 - 9, 2007


Heinz W. Engl, RICAM & Johannes Kepler University Linz, Austria
Christoph Flamm, University of Vienna, Austria
Philipp Kügler, RICAM & Johannes Kepler University Linz, Austria
Peter Schuster, University of Vienna, Austria

Workshop Abstract

Systems biology is heading for a description of the functional relations of all players in an entire cell or an organism by means of chemical reaction kinetics, i.e., complete genetic and metabolic reaction network are the subject of mathematical analysis, modeling, and simulation. Although analysis and modeling of whole cells is still out of reach, modules or semi-autonomous regulation and reaction subnetworks are studied successfully and provide an understanding of important quantities which are characteristic for living systems, e.g., robustness, homeostasis and long term stability of periods. The great challenge of systems biology comes from the large numbers of reactions, often several thousands and more, as well as a similarly large number of parameters, many of which are unknown, leading to high dimensional ODEs. High-throughput data of cells at the genomic, proteomic and metabolic levels provide an enormous amount of information on the dynamics of functioning cells. During the special semester we focus on mathematical methods to infer the functional network at genomic or metabolic level from such time series data. Problems to be studied include the calcium dynamics during T-cell activation, the analysis of stoichiometric networks and the evolution of metabolic networks.

Confirmed Speakers

Bree Aldridge, Massachusetts Institute of Technology, USA
Jaydeep Bardhan, Argonne National Laboratory, USA
Paul Barton, Massachusetts Institute of Technology, USA
Luca Cardelli, Microsoft Research Cambridge, UK
Attila Csikasz-Nagy, University of Trento, Italy
Hidde De Jong, INRIA Rhône-Alpes, France
Willy Govaerts, Ghent University, Belgium
Markus Hegland, Australian National University, Australia
Mats Jirstrand, Fraunhofer-Chalmers Research Centre for Industrial Mathematics, Sweden
Edda Klipp, Max Planck Institute for Molecular Genetics, Germany
David Kreil, University of Natural Resources and Applied Life Sciences, Austria
James Lu, RICAM, Austria
John Lu, National Institute of Standards & Technology, USA
Julie Mitchell, University of Wisconsin-Madison, USA
Martin Moennigmann, Aachen University of Technology, Germany
Stefan Müller, RICAM, Austria
Antonis Papachristodoulou, University of Oxford, UK
Peter Schuster, University of Vienna, Austria
Stefan Schuster, Friedrich-Schiller-University Jena, Germany
Bruce Shapiro, The Beckman Institute at Caltech, USA
Peter Sykacek, BOKU University, Austria
Bruce Tidor, Massachusetts Institute of Technology, USA
Katharina Wilkins, Massachusetts Institute of Technology, USA
Jason Zwolak, Virginia Tech, USA

Time Schedule Workshop on Systems Biology

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