Former Member

Prof. Dr. Philipp Kügler

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Philipp Kügler

Peer Reviewed Journal Publication
  • Kügler, Philipp (2016) Early afterdepolarizations with growing amplitudes via delayed subcritical Hopf bifurcations and unstable manifolds of saddle foci in cardiac action potential dynamics. PLoS ONE, Bd. 11, S. 1-14.
  • Hsiao Y-T, Lee W-P, Yang W, Müller S, Flamm C, Hofacker I, Kügler P (2015, online: 2015) Practical Guidelines for Incorporating Knowledge-Based and Data-Driven Strategies into the Inference of Gene Regulatory Networks. IEEE/ACM Transactions on Computational Biology and Bioinformatics (99), S. 1-13. (link)
  • Philipp Kügler, Wei Yang (2014, online: 2013) Identification of alterations in the Jacobian of biochemical reaction networks from steady state covariance data at two conditions. Journal of Mathematical Biology, Bd. DOI 10.1007/s00285-013-0685-3, S. 1-27.
  • Wu, Xinming; Kügler, Philipp; Lu, Shuai (2014, online: 2014) Identification of the exchange coefficient from indirect data for a coupled continuum pipe-flow model. Chinese Annals of Mathematics, Series B, Bd. 35 (3), S. 483-500.
  • Stanislav Beyl, Philipp Kügler, Annette Hohaus, Katrin Depil, Steffen Hering, Eugen Timin (2014, online: 2013) Methods for quantification of pore–voltage sensor interaction in CaV 1.2. Pflügers Archiv - European Journal of Physiology (466(2)), S. 265-74.
  • Clemens A Zarzer, Martin Puchinger, Gottfried Köhler, Philipp Kügler (2013, online: 2013) Differentiation between genomic and non-genomic feedback controls yields an HPA axis model featuring Hypercortisolism as an irreversible bistable switch. Theoretical Biology and Medical Modelling.
  • Martin Gerald Puchinger, Clemens Alexander Zarzer, Philipp Kügler, Erwin Gaubitzer, Gottfried Köhler (2012, online: 2012) In vitro detection of adrenocorticotropic hormone levels by fluorescence correlation spectroscopy immunoassay for mathematical modeling of glucocorticoid-mediated feedback mechanisms. EURASIP Journal on Bioinformatics and Systems Biology.
  • Kügler, Philipp (2012, online: 2012) Moment fitting for parameter inference in repeatedly and partially observed stochastic biological models. PLoS ONE, S. 1-15.
  • Kügler, Philipp (2012, online: 2012) A sparse update method for solving underdetermined systems of nonlinear equationsapplied to the manipulation of biological signaling pathways. SIAM Journal on Applied Mathematics, Bd. 72 (4), S. 982-1001.
  • Liudmila Erokhova, Andreas Horner, Philipp Kügler and Peter Pohl (2011, online: 2011) Monitoring Single-channel Water Permeability in Polarized Cells. Journal of Biological Chemistry, Bd. 286, S. 39926-39932.
  • Kügler, Philipp (2010) Online parameter identification without Ricatti type equation in a class of time-dependent partial differential equations: an extended state approach with potential to partial observations. Inverse Problems.
  • Engl HW, Flamm C, Kügler P, Lu J, Müller S, Schuster P (2009) Inverse Problems in Systems Biology. Inverse Problems, Bd. 25 (12), S. 1-51. (link)
  • John C. Mathai, Andreas Missner, Philipp Kügler, Sapar M. Saparov, Mark L. Zeidel, John K. Lee, Peter Pohl (2009) No facilitator required for membrane transport of hydrogen sulphide. PNAS, Bd. 106 (39), S. 16633-16638. (link)
  • Stanislav Beyl, Philipp Kügler, Michaela Kudrnac, Annette Hohaus, Steffen Hering, Eugen Timin (2009) Different pathways for activation and deactivation in Ca V 1.2: a minimal gating model. Journal of General Physiology, Bd. 134 (3), S. 231 - 241.
  • Philipp Kügler, Eva Sincich (2009) Logarithmic convergence rates for the identification of a nonlinear Robin coefficient. Journal of Mathematical Analysis and Applications, Bd. 359, S. 451--463.
  • Philipp Kügler, Erwin Gaubitzer, Stefan Müller (2009) Parameter identification for chemical reaction systems using sparsity enforcing regularization - a case study for the Chlorite - Iodide reaction. Journal of Physical Chemistry A, Bd. 113 (12), S. 2775-85. (link)
  • Andreas Missner, Philipp Kügler, Yuri N. Antonenko, Peter Pohl (2008) Passive transport across bilayer lipid membranes: Overton continues to rule. PNAS, Bd. 105 (52), S. E123. (link)
  • Andreas Missner, Philipp Kügler, Sapar M. Saparov, Klaus Sommer, John C. Mathai, Mark L. Zeidel, Peter Pohl (2008) Carbon dioxide transport through membranes. Journal of Biological Chemistry, Bd. 283, S. 25340-25347. (link)
  • Kügler, Philipp (2008) Online parameter identification in time-dependent differential equations as a nonlinear inverse problem. European Journal of Applied Mathematics, Bd. 19, S. 479--506.
  • Xinming Wu, Philipp Kügler, Shuai Lu Identification of the exchange coefficient from indirect data for a coupled continuum pipe-flow model. Springer Chinese Annals of Mathematics Ser. B.
  • S. Beyl, P. Kügler, E. Timin, S. Hering (online: 2015 Direct estimation of CaV1.2 gating parameters: quantification of voltage sensor - pore transductions and their modulation by FLP 64176. Current Molecular Pharmacology, Bd. -, S. -.

Book/Monograph
  • Philipp Kügler, W. Windsteiger (2012, online: 2012) Algorithmische Methoden II - Funktionen, Matrizen, Multivariate Polynome. In Reihe: Mathematik kompakt: Birkhäuser.
  • Philipp Kügler, Wolfgang Windsteiger (2009, online: 2009) Algorithmische Methoden I - Zahlen, Vektoren, Polynome. In Reihe: Mathematik kompakt: Birkhäuser.
  • (2008) Algorithmische Methoden Band 1: Zahlen, Vektoren, Polynome. In Reihe: Mathematik Kompakt: Birkhäuser.

Conference Contribution: Publication in Proceedings
  • (2008) Online identification of nonlinearities in time dependent differential equations.
  • Kügler, Philipp (2008) Online identification of nonlinearities in time dependent differential equations., Journal of Physics (International Conference on Inverse Problems in .. Problems in Engineering: Theory and Practice) In Reihe: Conference Series, Bd. 19, S. 135 / 012059.

Contribution in Collection
  • Smetana, Walter and Balluch, Bruno and Atassi, Ibrahim and Kügler, Philipp and Gaubitzer, Erwin and Edetsberger, Michael and Köhler, Gottfried (2010, online: 2010) A Ceramic Microfluidic Device for Monitoring Complex Biochemical Reactive Systems., Biomedical Engineering Systems and Technologies: Springer.
  • Heinz W. Engl, Philipp Kügler (2005) Nonlinear Inverse Problems: Theoretical Aspects and Some Industrial Applications. In: V. Capasso, J. Periaux (Hrsg.), Multidisciplinary Methods for Analysis, Optimization and Control of Complex Systems: Springer Heidelberg, S. 3-48.

Habilitation
  • Kügler, Philipp (2013, online: 2013) Inverse Problems for Differential Equations with Partial State Observations and Applications in Mathematical Physiology.

Editorship
  • (2008) Carbon dioxide transport through membranes.
  • (2008) Online parameter identification in time-dependent differential equations as a nonlinear inverse problem.

Research Report
  • Kügler, Philipp (2015) Early afterdepolarizations with growing amplitudes do not require stable limit cycles in the fast subsystem of cardiac action potential models. Bericht-Nr. 17-2015; RICAM:.

Other Publication
  • (2008) Passive transport across bilayer lipid membranes: Overton continues to rule.