SBML model of Cell cycle control mechanism

This is a hypothetical model of the cell cycle control mechanism by Chen et al(2004). The model reproduces the time profiles of the different species in Fig 2 of the paper. The figure depicts the cycle of a daughter cell. Since,the Mass Doubling Time(MDT) is 90 minutes, time t=90 from the model simulation will correspond to time t=0 in the paper. The model was successfully tested using MathSBML

This model originates from BioModels Database: A Database of Annotated Published Models. It is copyright (c) 2005-2006 The BioModels Team.
For more information see the terms of use.

 Chen Katherine C kchen@vt.edu Department of Biology, Virginia Polytechnic Institute Dharuri Harish hdharuri@cds.caltech.edu California Institute of Technology 2006-05-08T12:05:34 2006-06-07T15:16:10 A1 A2 A3 A4 A2 A1 A3 A2 A4 A1 A1 A2 A3 A4 2 A4 A1 BB_218 A1 A2 A3 A4 2 BB_218 A1 A2 A3 A4 2 4 A2 A1 A4 A1 M1 J1 k1 S1 k1 S1 M1 J1 S1 k1 S1 S2 k1 S1 S2 k1 S1 k1 S1 k1 k1 b0_75 MASS_37 kisbf_178 kisbf_179 CLB2_20 C0_78 Dn3_80 MASS_37 Jn3_118 Dn3_80 MASS_37 kppc1_183 CDC14_8 kppf6_184 CDC14_8 kaiep_128 CLB2_20 kacdh_126 kacdh_127 CDC14_8 kicdh_174 kicdh_175 eicdhn3_97 CLN3_25 eicdhn2_96 CLN2_24 eicdhb5_95 CLB5_22 eicdhb2_94 CLB2_20 kkpnet_181 kkpnet_182 CDC15_10 MASS_37 kppnet_185 kppnet_186 PPX_46 kasbf_132 esbfn2_101 CLN2_24 esbfn3_102 CLN3_25 BCK2_1 esbfb5_100 CLB5_22 GK_219 Vasbf_60 Visbf_68 Jasbf_109 Jisbf_116 GK_219 kamcm_129 CLB2_20 kimcm_177 Jamcm_108 Jimcm_115 2 mdt_216 1.026 mu_39 32 mu_39 D_26 kd2c1_144 ec1n3_88 CLN3_25 ec1k2_86 BCK2_1 ec1n2_87 CLN2_24 ec1b5_85 CLB5_22 ec1b2_84 CLB2_20 kd2f6_145 ef6n3_93 CLN3_25 ef6k2_91 BCK2_1 ef6n2_92 CLN2_24 ef6b5_90 CLB5_22 ef6b2_89 CLB2_20 kd1c1_140 Vd2c1_61 Jd2c1_111 SIC1_50 C2_4 C5_6 SIC1P_51 C2P_5 C5P_7 kd1f6_141 Vd2f6_62 Jd2f6_112 CDC6_14 F2_29 F5_31 CDC6P_15 F2P_30 F5P_32 kdb_150 kdb_151 CDH1_17 kdb2p_152 CDC20_12 kdb_153 kdb_154 CDC20_12 kdpds_142 kdpds_146 CDC20_12 kdpds_149 CDH1_17 kdppx_167 kdppx_168 J20ppx_105 CDC20_12 Jpds_119 Jpds_119 PDS1_44 CLB2_20 C2_4 C2P_5 F2_29 F2P_30 CLB5_22 C5_6 C5P_7 F5_31 F5P_32 CDC14_8 RENT_47 RENTP_48 NET1_40 NET1P_41 RENT_47 RENTP_48 SIC1_50 C2_4 C5_6 SIC1P_51 C2P_5 C5P_7 CDC6_14 F2_29 F5_31 CDC6P_15 F2P_30 F5P_32 SIC1T_52 CDC6T_16 CDC15_10 CDC15i_11 CDC15T_79 IE_33 IEP_34 IET_104 ESP1_27 PE_45 ESP1T_103 TEM1GDP_56 TEM1GTP_57 TEM1T_217 Mass_Action_0_223 mu_39 MASS_37 Mass_Action_0_223 ksn_203 ksn_204 SBF_49 MASS_37 Mass_Action_1_222 kdn2_164 CLN2_24 Mass_Action_0_223 ksb_192 ksb_193 MCM1_38 MASS_37 Mass_Action_1_222 Vdb2_63 CLB2_20 Mass_Action_0_223 ksb_194 ksb_195 SBF_49 MASS_37 Mass_Action_1_222 Vdb5_64 CLB5_22 Mass_Action_0_223 ksc_197 ksc_198 SWI5_54 Mass_Action_1_222 Vkpc1_69 SIC1_50 Mass_Action_1_222 Vppc1_72 SIC1P_51 Mass_Action_1_222 kd3c1_147 SIC1P_51 Mass_Action_2_221 kasb2_130 CLB2_20 SIC1_50 Mass_Action_1_222 kdib2_157 C2_4 Mass_Action_2_221 kasb5_131 CLB5_22 SIC1_50 Mass_Action_1_222 kdib5_158 C5_6 Mass_Action_1_222 Vkpc1_69 C2_4 Mass_Action_1_222 Vppc1_72 C2P_5 Mass_Action_1_222 Vkpc1_69 C5_6 Mass_Action_1_222 Vppc1_72 C5P_7 Mass_Action_1_222 Vdb2_63 C2_4 Mass_Action_1_222 Vdb5_64 C5_6 Mass_Action_1_222 kd3c1_147 C2P_5 Mass_Action_1_222 kd3c1_147 C5P_7 Mass_Action_1_222 Vdb2_63 C2P_5 Mass_Action_1_222 Vdb5_64 C5P_7 Mass_Action_0_223 ksf_200 ksf_201 SWI5_54 ksf_202 SBF_49 Mass_Action_1_222 Vkpf6_70 CDC6_14 Mass_Action_1_222 Vppf6_73 CDC6P_15 Mass_Action_1_222 kd3f6_148 CDC6P_15 Mass_Action_2_221 kasf2_134 CLB2_20 CDC6_14 Mass_Action_1_222 kdif2_160 F2_29 Mass_Action_2_221 kasf5_135 CLB5_22 CDC6_14 Mass_Action_1_222 kdif5_161 F5_31 Mass_Action_1_222 Vkpf6_70 F2_29 Mass_Action_1_222 Vppf6_73 F2P_30 Mass_Action_1_222 Vkpf6_70 F5_31 Mass_Action_1_222 Vppf6_73 F5P_32 Mass_Action_1_222 Vdb2_63 F2_29 Mass_Action_1_222 Vdb5_64 F5_31 Mass_Action_1_222 kd3f6_148 F2P_30 Mass_Action_1_222 kd3f6_148 F5P_32 Mass_Action_1_222 Vdb2_63 F2P_30 Mass_Action_1_222 Vdb5_64 F5P_32 Mass_Action_0_223 ksswi_210 ksswi_211 MCM1_38 Mass_Action_1_222 kdswi_170 SWI5_54 Mass_Action_1_222 kdswi_170 SWI5P_55 Mass_Action_1_222 kaswi_138 CDC14_8 SWI5P_55 Mass_Action_1_222 kiswi_180 CLB2_20 SWI5_54 MichaelisMenten_220 Vaiep_59 Jaiep_107 1 IE_33 MichaelisMenten_220 1 Jiiep_114 kiiep_176 IEP_34 Mass_Action_0_223 ks_189 ks_190 MCM1_38 Mass_Action_1_222 kd20_143 CDC20i_13 Mass_Action_1_222 kd20_143 CDC20_12 Mass_Action_1_222 ka_124 ka_125 IEP_34 CDC20i_13 Mass_Action_1_222 MAD2_36 CDC20_12 Mass_Action_0_223 kscdh_199 Mass_Action_1_222 kdcdh_156 CDH1_17 Mass_Action_1_222 kdcdh_156 CDH1i_18 MichaelisMenten_220 Vacdh_58 Jacdh_106 1 CDH1i_18 MichaelisMenten_220 Vicdh_67 Jicdh_113 1 CDH1_17 Mass_Action_0_223 ks14_187 Mass_Action_1_222 kd14_139 CDC14_8 Mass_Action_2_221 kasrent_136 CDC14_8 NET1_40 Mass_Action_1_222 kdirent_162 RENT_47 Mass_Action_2_221 kasrentp_137 CDC14_8 NET1P_41 Mass_Action_1_222 kdirentp_163 RENTP_48 Mass_Action_0_223 ksnet_205 Mass_Action_1_222 kdnet_165 NET1_40 Mass_Action_1_222 kdnet_165 NET1P_41 Mass_Action_1_222 Vkpnet_71 NET1_40 Mass_Action_1_222 Vppnet_74 NET1P_41 Mass_Action_1_222 Vkpnet_71 RENT_47 Mass_Action_1_222 Vppnet_74 RENTP_48 Mass_Action_1_222 kdnet_165 RENT_47 Mass_Action_1_222 kdnet_165 RENTP_48 Mass_Action_1_222 kd14_139 RENT_47 Mass_Action_1_222 kd14_139 RENTP_48 MichaelisMenten_220 LTE1_35 Jatem_110 1 TEM1GDP_56 MichaelisMenten_220 BUB2_2 Jitem_117 1 TEM1GTP_57 Mass_Action_1_222 ka_121 TEM1GDP_56 ka_122 TEM1GTP_57 ka15p_123 CDC14_8 CDC15i_11 Mass_Action_1_222 ki15_173 CDC15_10 Mass_Action_0_223 ksppx_208 Mass_Action_1_222 Vdppx_66 PPX_46 Mass_Action_0_223 kspds_207 kspds_188 SBF_49 kspds_191 MCM1_38 Mass_Action_1_222 Vdpds_65 PDS1_44 Mass_Action_1_222 Vdpds_65 PE_45 Mass_Action_2_221 kasesp_133 PDS1_44 ESP1_27 Mass_Action_1_222 kdiesp_159 PE_45 Mass_Action_0_223 ksori_206 eorib5_99 CLB5_22 eorib2_98 CLB2_20 Mass_Action_1_222 kdori_166 ORI_43 Mass_Action_0_223 ksbud_196 ebudn2_82 CLN2_24 ebudn3_83 CLN3_25 ebudb5_81 CLB5_22 Mass_Action_1_222 kdbud_155 BUD_3 Mass_Action_0_223 ksspn_209 CLB2_20 Jspn_120 CLB2_20 Mass_Action_1_222 kdspn_169 SPN_53 CLB2_20 CLB5_22 KEZ2_172 0 0 ORI_43 1 0 mad2h_214 bub2h_76 SPN_53 1 0 mad2l_215 lte1h_212 bub2l_77 CLB2_20 KEZ_171 0 F_28 MASS_37 lte1l_213 0 0